PROTECTION ACTIVITY OF T CELL LYMPHOKINES AGAINST INFECTIOUS BURSAL DISEASE IN LAYER PULLETS
نویسندگان
چکیده
The present study was aimed to administering hyperimmunized avian salmonella-immune lymphokines (S-ILK) 200 one-day-old layer pullets improve the immunological response against Gumboro (IBDV) divided into four groups. On first day, following applied all groups: G1: intraperitoneal injection of 0.50 mL S-ILK followed by a 30-minute challenge with 0.1 IBDV (ELD50 103.2); G2: 0.5 S-NILK IBDV. G3: challenged only, G4: uninfected, unchallenged group consider as negative control. results findings indicated greatest statistically significant rise (p≤ 0.05) in IgG and IFN-γ titres that viral load test revealed at 7 14 days after infection, largest number RNA copies were found G2 G3. bursa Fabricius. had lowest mortality rate compared other Early administration improves maternal resistance infection inhibits replication fabricius challenge. Thus, we may reduce amount time, effort, money spent on immunization procedures do not completely protect diseases.
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ژورنال
عنوان ژورنال: The Iraqi Journal of Agricultural science
سال: 2023
ISSN: ['2410-0862', '0075-0530']
DOI: https://doi.org/10.36103/ijas.v54i4.1804